{"id":1840,"date":"2018-06-21T21:07:00","date_gmt":"2018-06-22T01:07:00","guid":{"rendered":"https:\/\/nanobiotix.com\/resource\/estro-hafnium-oxide-nanoparticles-and-radiotherapy-a-promising-new-treatment-strategy\/"},"modified":"2024-10-29T08:50:26","modified_gmt":"2024-10-29T12:50:26","slug":"estro-hafnium-oxide-nanoparticles-and-radiotherapy-a-promising-new-treatment-strategy","status":"publish","type":"resource","link":"https:\/\/nanobiotix.com\/fr\/resource\/estro-hafnium-oxide-nanoparticles-and-radiotherapy-a-promising-new-treatment-strategy\/","title":{"rendered":"ESTRO – Hafnium Oxide Nanoparticles and Radiotherapy: A Promising New Treatment Strategy"},"content":{"rendered":"

[vc_row padding_top=”0″ padding_bottom=”0″ section_container_layout=”full-width” remove_horizontal_padding=”yes” module_type=”bg-color” gutter_size=”yes” equal_height=”yes” bg_color=”#28282e”][vc_column][vc_row_inner padding_top=”0″ padding_bottom=”0″ gutter_size=”yes” equal_height=”yes”][vc_column_inner column_paddings=”105″ column_position_vertical=”middle” column_min_height=”700″ column_min_height_sm=”400″ column_min_height_xs=”350″ module_type=”bg-image” bg_image=”102″ mask_fx=”yes-mask” mask_color_mode=”palette” mask_bg_color_palette=”main-mask” animation_fx=”yes-animation” animation_delay=”200″ animation_offset_scroll_down=”90″ width=”1\/2″ animation_in=”fadeInUp”][vc_empty_space height=”60px” responsive_lg=”hidden” responsive_md=”hidden”][az_box_icons box_icon_title=”Authors” box_icon_color_mode=”on-the-fly” icon_visibility=”yes-icon” icon_type=”font” icon=”fa fa-edit” icon_color_mode=”on-the-fly” icon_size=”50″ box_icon_color=”#ffffff” icon_color=”#ffffff”]Le Tourneau C.1<\/span>, Le Pechoux C.2<\/span>, Kantor G.3<\/span>, Carrere S.4<\/span>, Bonvalot S.1<\/span>, Le Prise E.5<\/span>, Nguyen F.2<\/span>, Baumann A. S.6<\/span>, Vendrely V.7<\/span>, Bronowicki J. P.8<\/span>, Moreno-Garcia V.9<\/span>, Delannes M.10<\/span>, Thariat J.11<\/span>, Papai Z.12<\/span>, Ruthowski P.13<\/span>, Tiangco B.14<\/span>, Rastrelli M.15<\/span>, Agoston P.16<\/span>, Sunyach M.P.17<\/span>, Rubi Li K.18<\/span>, Mervoyer A.19<\/span>, Sy-Ortin T.20<\/span>, Hong A.21<\/span>, Anghel R.22<\/span>, Gronchi A.23<\/span> 1 – Institut Curie, Oncology, Paris, France 2 – Institut Gustave Roussy, Oncology, Villejuif, France 3 – Institut Bergoni\u00e9, Oncology, Bordeaux, France 4 – ICM, Oncology, Montpellier, France 5 – Eug\u00e8ne Marquis, Oncology, Rennes, France 6 – Canc\u00e9rologie de Lorraine, Oncology, Nancy, France 7 – H\u00f4pital du Haut-L\u00e9v\u00eaque, Oncology, Bordeaux, France 8 – H\u00f4pitaux de Brabois CHU Nancy, Oncology, Nancy, France 9 – START Madrid, Oncology, Madrid, Spain 10 – Claudius Regaud, Oncology, Toulouse, France 11 – Antoine Lacassagne, Oncology, Nice, France 12 – Medical Centre- Hungarian Defence Forces, Oncology, Budapest, Hungary 13 – Maria Sklodowska-Curie Institute – Oncology Center, Warsaw, Poland 14 – The Medical City, Oncology, Pasig City, Philippines 15 – Veneto institute of oncology, Padua Italy 16 – Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Oncology, Budapest, Hungary 17 – Centre L\u00e9on B\u00e9rard, Oncology, Lyon, France 18 – St. Luke\u2019s Medical Center, Oncology, Quezon City, Philippines 19 – Centre Rene Gauducheau- CLCC Nantes Atlantique, Oncology, St Herblain, France 20 – University of Santo Thomas, Oncology, Manila, Philippines 21 – Chris O\u2019Brien Lifehouse, Oncology, Sidney, Australia 22 – Institutul Oncologic Bucuresti- \u201cProf. Dr. Alexandru Trestioreanu\u201d, Oncology, Bucharest, Romania 23 – Fondazione IRCCS Istituto Nazionale dei Tumori, Oncology, Milan, Italy<\/span>[\/az_box_icons][vc_empty_space height=”60px” responsive_lg=”hidden” responsive_md=”hidden”][\/vc_column_inner][vc_column_inner column_paddings=”105″ column_position_vertical=”middle” module_type=”bg-color” animation_fx=”yes-animation” animation_delay=”300″ animation_offset_scroll_down=”90″ width=”1\/2″ bg_color=”#ffffff” animation_in=”fadeInUp”][vc_empty_space height=”60px” responsive_lg=”hidden” responsive_md=”hidden”][az_box_icons box_icon_title=”Summary” icon_visibility=”yes-icon” icon_type=”font” icon=”az-icon az-icon-layers2″ icon_color_mode=”on-the-fly” icon_color=”#28282e” icon_size=”50″]With recent advances in radiation delivery techniques, an increasing number of cancer patients undergo radiotherapy. However, due to the non-targeted nature of radiotherapy, doses are limited by potential toxicity to surrounding normal tissue. Thus, a major challenge remains to develop new strategies to improve the tumor selectivity of radiation therapy. Nanobiotix has developed NBTXR3 – a hafnium oxide nanoparticle that can enter tumor cells and deposit high levels of energy in cells when exposed to ionizing radiation thereby increasing tumor-specific physical killing through DNA damage\/cell destruction and enhancing the intratumoral immune profile. At 2018 ESTRO<\/em>, an overview of NBTXR3 was presented, describing its role in current 7 clinical trials.[\/az_box_icons][vc_empty_space height=”60px” responsive_lg=”hidden” responsive_md=”hidden”][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n","protected":false},"featured_media":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"wds_primary_resource_type":0,"wds_primary_data_type":0,"wds_primary_indication":0,"wds_primary_platform_type":0,"footnotes":""},"resource_type":[31],"data_type":[25],"indication":[26,32,33,27],"platform_type":[36],"class_list":["post-1840","resource","type-resource","status-publish","hentry","resource_type-abstracts","data_type-clinical","indication-head-neck","indication-liver","indication-rectum","indication-sts","platform_type-nbtxr3"],"acf":[],"_links":{"self":[{"href":"https:\/\/nanobiotix.com\/fr\/wp-json\/wp\/v2\/resource\/1840","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nanobiotix.com\/fr\/wp-json\/wp\/v2\/resource"}],"about":[{"href":"https:\/\/nanobiotix.com\/fr\/wp-json\/wp\/v2\/types\/resource"}],"version-history":[{"count":0,"href":"https:\/\/nanobiotix.com\/fr\/wp-json\/wp\/v2\/resource\/1840\/revisions"}],"wp:attachment":[{"href":"https:\/\/nanobiotix.com\/fr\/wp-json\/wp\/v2\/media?parent=1840"}],"wp:term":[{"taxonomy":"resource_type","embeddable":true,"href":"https:\/\/nanobiotix.com\/fr\/wp-json\/wp\/v2\/resource_type?post=1840"},{"taxonomy":"data_type","embeddable":true,"href":"https:\/\/nanobiotix.com\/fr\/wp-json\/wp\/v2\/data_type?post=1840"},{"taxonomy":"indication","embeddable":true,"href":"https:\/\/nanobiotix.com\/fr\/wp-json\/wp\/v2\/indication?post=1840"},{"taxonomy":"platform_type","embeddable":true,"href":"https:\/\/nanobiotix.com\/fr\/wp-json\/wp\/v2\/platform_type?post=1840"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}